???????????????????????????????0.57%??21955??????????????0.23%??4895???????????2%??5000??????????????????????????????????2.7%??????????????1.2%?????????????????????β??????8%????CRO??????????????????????к???????3%???к?????2%?????????????????????????????????6%???????ɡ?????ɡ?????????ɡ?????????ɡ?????????ɡ???????????????????????????100%-130%?????????????5%??